Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 5/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036508 | 0.91 | NCF1 (0.48) | GNAO1NCF1GBA1GNAI3GNAI1 | |
| SCHEMBL19442433 | 0.88 | SLC6A1 (0.41) | GNAO1NCF1GBA1CYP2D6CYP1A2 | |
| SCHEMBL27267697 | 0.87 | GNAO1 (0.36) | GNAO1GBA1GNAI3GNAI1SLC6A1 | |
| SCHEMBL25565871 | 0.84 | NCF1 (0.54) | GNAO1NCF1GNAI3GNAI1CYP2D6 | |
| SCHEMBL22859167 | 0.84 | NCF1 (0.54) | GNAO1NCF1GNAI3GNAI1CYP2D6 | |
| SCHEMBL25566048 | 0.84 | NCF1 (0.54) | GNAO1NCF1GNAI3GNAI1CYP2D6 | |
| SCHEMBL12371223 | 0.84 | NCF1 (0.52) | NCF1CYP2D6CYP1A2ACHEHRH4 | |
| SCHEMBL22047606 | 0.84 | NCF1 (0.42) | GNAO1NCF1GNAI3GNAI1CYP2D6 | |
| SCHEMBL23416766 | 0.82 | NCF1 (0.43) | GNAO1NCF1ACHEHRH4HRH3 | |
| SCHEMBL25569153 | 0.82 | NCF1 (0.43) | GNAO1NCF1ACHEHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |