Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473819 | 0.95 | SLC6A2 (0.37) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL5645558 | 0.95 | NOS3 (0.33) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL27391655 | 0.93 | NOS3 (0.35) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL3474532 | 0.93 | SLC6A2 (0.36) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL5651239 | 0.90 | ADRA1B (0.39) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL27564858 | 0.90 | ADRA1B (0.42) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL24351757 | 0.88 | NOS3 (0.42) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL24350727 | 0.88 | NOS3 (0.42) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL24480738 | 0.86 | NOS3 (0.33) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL24319629 | 0.84 | ADRA1B (0.31) | ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |