Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645558 | 0.84 | NOS3 (0.33) | ADRA1B | |
| SCHEMBL25565965 | 0.84 | NOS3 (0.36) | ADRA1B | |
| SCHEMBL27391655 | 0.82 | NOS3 (0.35) | ADRA1B | |
| SCHEMBL24320683 | 0.80 | TDP1 (0.32) | — | |
| SCHEMBL3473819 | 0.79 | SLC6A2 (0.37) | ADRA1B | |
| SCHEMBL5651239 | 0.78 | ADRA1B (0.39) | ADRA1B | |
| Hydrochloric Acid SCHEMBL3474532 | 0.78 | SLC6A2 (0.36) | ADRA1B | |
| SCHEMBL24319183 | 0.76 | NCF1 (0.41) | ADRA1B | |
| SCHEMBL12717990 | 0.76 | NCF1 (0.41) | ADRA1B | |
| SCHEMBL27564858 | 0.74 | ADRA1B (0.42) | ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |