Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12141653 | 0.96 | GABRP (0.41) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL25569231 | 0.87 | GABRP (0.39) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL11616 | 0.84 | SLC6A4 (0.46) | CYP2D6SLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL17961728 | 0.84 | SLC6A4 (0.46) | CYP2D6SLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL17961761 | 0.84 | SLC6A4 (0.46) | CYP2D6SLC6A4KCNH2SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL21772854 | 0.82 | SLC6A4 (0.44) | CYP2D6SLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL21772847 | 0.81 | SLC6A4 (0.44) | TSHRCYP2D6KMT2ASLC6A4KCNH2 | |
| SCHEMBL40096 | 0.80 | GABRA1 (0.52) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL13903027 | 0.80 | GLI1 (0.38) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL17192615 | 0.80 | DPP4 (0.43) | TSHRKCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |