Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.65 |
| ▸ | HTR2C | P28335 | 6/20 | 0.62 |
| ▸ | HTR2B | P41595 | 6/20 | 0.62 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.61 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | TSPO | P30536 | 1/20 | 0.57 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21710880 | 1.00 | ADORA3 (0.65) | ADORA3ADORA1HTR2CHTR2BP2RY1 | |
| SCHEMBL19464999 | 0.91 | P2RY1 (0.57) | ADORA3ADORA1HTR2CHTR2BP2RY1 | |
| SCHEMBL19459478 | 0.89 | HTR2C (0.66) | ADORA3ADORA1HTR2CHTR2BTMIGD3 | |
| SCHEMBL26934885 | 0.84 | HSP90B1 (0.76) | ADORA3ADORA1HTR2CHTR2BP2RY1 | |
| SCHEMBL19464932 | 0.84 | HSP90B1 (0.76) | ADORA3ADORA1HTR2CHTR2BP2RY1 | |
| SCHEMBL19464935 | 0.84 | HSP90B1 (0.76) | ADORA3ADORA1HTR2CHTR2BP2RY1 | |
| SCHEMBL21257345 | 0.83 | P2RY1 (0.54) | ADORA3ADORA1P2RY1 | |
| SCHEMBL3738112 | 0.79 | ADORA3 (1.00) | ADORA3ADORA1HTR2BTMIGD3ADORA2A | |
| SCHEMBL23098401 | 0.78 | P2RY1 (0.73) | ADORA3ADORA1HTR2CHTR2BP2RY1 | |
| SCHEMBL19799168 | 0.78 | P2RY1 (0.73) | ADORA3ADORA1HTR2CHTR2BP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091791-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |