Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | CSF1R | P07333 | 9/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567190 | 0.82 | EGFR (0.49) | EGFRHPGDMAPK14CSF1RFLT3 | |
| SCHEMBL25567722 | 0.76 | MAPK14 (0.46) | HPGDMAPK14CSF1RFLT3MEN1 | |
| SCHEMBL25564759 | 0.76 | MAPK14 (0.58) | MAPK14CSF1RFLT3MEN1NPC1 | |
| SCHEMBL25567126 | 0.74 | EGFR (0.49) | EGFRHPGDMAPK14FLT3MEN1 | |
| SCHEMBL25567562 | 0.73 | HPGD (0.47) | HPGDMAPK14CSF1RFLT3MEN1 | |
| SCHEMBL25565785 | 0.72 | RAF1 (0.49) | HPGDMAPK14CSF1RFLT3MEN1 | |
| SCHEMBL25567184 | 0.70 | CSF1R (0.54) | CSF1R | |
| SCHEMBL14422913 | 0.67 | EGFR (0.72) | EGFRHPGDMAPK14FLT3MEN1 | |
| SCHEMBL4104287 | 0.66 | EGFR (0.70) | EGFRHPGDMAPK14FLT3MEN1 | |
| SCHEMBL4102589 | 0.66 | EGFR (0.74) | EGFRHPGDMAPK14FLT3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |