Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 7/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567722 | 0.89 | MAPK14 (0.46) | HPGDMAPK14CSF1RFLT3MEN1 | |
| SCHEMBL25564759 | 0.89 | MAPK14 (0.58) | MAPK14CSF1RFLT3MEN1NPC1 | |
| SCHEMBL25567190 | 0.87 | EGFR (0.49) | HPGDMAPK14CSF1RFLT3MEN1 | |
| SCHEMBL25567547 | 0.77 | HPGD (0.61) | HPGDMAPK14FLT3MEN1NPC1 | |
| SCHEMBL25565993 | 0.74 | ALDH1A1 (0.58) | FLT3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25567124 | 0.73 | EGFR (0.46) | HPGDMAPK14CSF1RFLT3MEN1 | |
| SCHEMBL25567247 | 0.73 | MAPK14 (0.59) | MAPK14CSF1RFLT3RAF1TRPV1 | |
| SCHEMBL25567538 | 0.73 | HPGD (0.59) | HPGDMAPK14MEN1NPC1RAB9A | |
| SCHEMBL25565806 | 0.72 | RAB9A (0.58) | MAPK14CSF1RFLT3MEN1NPC1 | |
| SCHEMBL10576398 | 0.71 | CMA1 (0.49) | MEN1KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |