Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567722 | 0.89 | MAPK14 (0.46) | FLT3HPGDMAPK14CSF1RMEN1 | |
| SCHEMBL25564759 | 0.89 | MAPK14 (0.58) | FLT3MAPK14CSF1RMEN1NPC1 | |
| SCHEMBL25567562 | 0.87 | HPGD (0.47) | FLT3HPGDMAPK14CSF1RMEN1 | |
| SCHEMBL25567124 | 0.82 | EGFR (0.46) | EGFRFLT3HPGDMAPK14CSF1R | |
| SCHEMBL25567126 | 0.81 | EGFR (0.49) | EGFRFLT3HPGDMAPK14MEN1 | |
| SCHEMBL15328229 | 0.75 | CASP3 (0.49) | FLT3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25565993 | 0.75 | ALDH1A1 (0.58) | FLT3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25567247 | 0.74 | MAPK14 (0.59) | FLT3MAPK14CSF1RRAF1 | |
| SCHEMBL25565806 | 0.73 | RAB9A (0.58) | FLT3MAPK14CSF1RMEN1NPC1 | |
| SCHEMBL10576398 | 0.72 | CMA1 (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |