SCHEMBL25567799

SCHEMBL25567799

OC(O)(O)c1ccc2c(c1)oc1ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 2/20 0.53
▸ MEN1 O00255 5/20 0.52
▸ KMT2A Q03164 5/20 0.52
▸ MAPT P10636 5/20 0.52
▸ KDM4E B2RXH2 5/20 0.52
▸ ALDH1A1 P00352 5/20 0.52
▸ HPGD P15428 4/20 0.52
▸ MAOA P21397 4/20 0.47
▸ SMN1; SMN2 Q16637 7/20 0.44
▸ NPC1 O15118 5/20 0.44
▸ RAB9A P51151 5/20 0.44
▸ TTR P02766 1/20 0.44
▸ LMNA P02545 3/20 0.43
▸ HSD17B10 Q99714 3/20 0.43
▸ GAA P10253 2/20 0.43
▸ HTR2B P41595 1/20 0.43
▸ HTT P42858 2/20 0.42
▸ GLA P06280 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ PGAM1 P18669 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1615693 0.81 AHR (0.53) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL24617992 0.81 AHR (0.53) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL18288034 0.77 AHR (0.49) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL19676925 0.75 AHR (0.47) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL31558552 0.74 NPC1 (0.50) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL571563 0.74 AHR (0.71) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL16919496 0.74 AHR (0.71) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL31153220 0.74 MAOA (0.79) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL2757860 0.74 MAOA (0.79) AHRMEN1KMT2AMAPTKDM4E
Dibenzofuran SCHEMBL8207 0.73 MAPT (0.68) AHRMEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 AHR 3008/4885MEN1 3817/4885KMT2A 4188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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