Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.73 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | ATF4 | P18848 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CCR2 | P41597 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24514196 | 0.92 | ADIPOR2 (0.73) | ADIPOR2ADIPOR1USP2ATF4POLB | |
| SCHEMBL17946118 | 0.91 | ADIPOR2 (0.88) | ADIPOR2ADIPOR1USP2ATF4POLB | |
| SCHEMBL17950883 | 0.90 | ADIPOR2 (0.90) | ADIPOR2ADIPOR1USP2ATF4POLB | |
| SCHEMBL25568934 | 0.90 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1USP2ATF4POLB | |
| SCHEMBL24514569 | 0.88 | ADIPOR2 (0.70) | ADIPOR2ADIPOR1USP2ATF4POLB | |
| SCHEMBL17656861 | 0.85 | ATF4 (0.86) | ATF4LMNASMN1; SMN2MAPK1KMT2A | |
| SCHEMBL17658492 | 0.85 | ATF4 (0.86) | ATF4LMNASMN1; SMN2MAPK1KMT2A | |
| SCHEMBL17950896 | 0.85 | POLB (0.63) | ADIPOR2ADIPOR1USP2POLBMCHR1 | |
| SCHEMBL17938602 | 0.84 | ADIPOR2 (1.00) | ADIPOR2ADIPOR1USP2POLBMCHR1 | |
| SCHEMBL17658584 | 0.84 | ATF4 (0.76) | ATF4POLBLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234923-A1 | USING ADIPONECTIN RECEPTOR AGONISTS TO TREAT INFLAMMATION AND BONE DISEASES IN DIABETES | TRUSTEES OF TUFTS COLLEGE | 2023-07-27 | — | — | US | disclosed |
| US-11655212-B2 | Using adiponectin receptor agonists to treat inflammation and bone diseases in diabetes | TRUSTEES OF TUFTS COLLEGE (US) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655212-B2 | Using adiponectin receptor agonists to treat inflammation and bone diseases in diabetes | ADIPOR1, ADIPOR2, GPR119 | ADIPOR2 2/4885ADIPOR1 1/4885USP2 3113/4885 |
| US-20230234923-A1 | USING ADIPONECTIN RECEPTOR AGONISTS TO TREAT INFLAMMATION AND BONE DISEASES IN DIABETES | ADIPOR1, ADIPOR2, GPR119 | ADIPOR2 2/4885ADIPOR1 1/4885USP2 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.