Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28328011 | 0.83 | SLC6A4 (0.37) | SLC6A4OPRM1HDAC4SLC6A3 | |
| SCHEMBL16031140 | 0.81 | HDAC4 (0.41) | HDAC4 | |
| SCHEMBL9770580 | 0.81 | OPRM1 (0.38) | OPRK1OPRM1 | |
| SCHEMBL25569167 | 0.79 | SLC6A4 (0.40) | SLC6A4GRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL11812076 | 0.78 | HDAC4 (0.47) | HDAC4 | |
| SCHEMBL16881740 | 0.76 | SIGMAR1 (0.57) | SIGMAR1TMEM97 | |
| SCHEMBL28647573 | 0.76 | KDM4E (0.35) | SLC6A4SLC6A3 | |
| SCHEMBL16029709 | 0.76 | HDAC4 (0.39) | OPRM1HDAC4 | |
| SCHEMBL11824501 | 0.75 | CCR2 (0.39) | LMNAHDAC4 | |
| SCHEMBL6390121 | 0.75 | OPRM1 (0.46) | SLC6A4OPRK1OPRM1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186889-A1 | LONG-ACTING AND LOW-ADDICTION COMPOUND AND PREPARATION METHOD THEREFOR | Shenzen Ruijian Biotechnology Co., Ltd. (CN) | 2023-05-31 | — | — | EP | disclosed |