SCHEMBL25569175

SCHEMBL25569175

COc1cccc(Nc2cccc(-c3ccc4ccccc4c3)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.53
RAPGEF4 Q8WZA2 1/20 0.53
ABCG2 Q9UNQ0 5/20 0.52
ABCB1 P08183 3/20 0.52
MAPT P10636 2/20 0.52
ABCC1 P33527 1/20 0.52
TP53 P04637 1/20 0.52
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
POLB P06746 2/20 0.51
MAPK1 P28482 1/20 0.51
PDE5A O76074 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2A6 P11509 1/20 0.50
PIK3CA P42336 1/20 0.49
PIK3CB P42338 1/20 0.49
PIK3CG P48736 1/20 0.49
TRPV1 Q8NER1 1/20 0.49
MTNR1A P48039 1/20 0.49
MTNR1B P49286 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20462471 0.92 CYP3A4 (0.47) PLAURAPGEF4ABCG2ABCB1MAPT
SCHEMBL20067339 0.87 MEN1 (0.60) RAPGEF4ABCG2ABCB1MAPTABCC1
SCHEMBL3400217 0.87 ALDH1A1 (0.63) RAPGEF4MAPTMEN1KMT2APOLB
SCHEMBL17550838 0.87 ALDH1A1 (0.61) MAPTMEN1KMT2ACYP1A2
SCHEMBL9534391 0.85 CYP1A2 (0.63) PLAUABCB1CYP1A2CYP2A6
SCHEMBL23868895 0.83 ALDH1A1 (0.68) MAPTMEN1KMT2AMAPK1
SCHEMBL30754067 0.83 ALDH1A1 (0.68) MAPTMEN1KMT2AMAPK1
SCHEMBL18271491 0.83 ALDH1A1 (0.62) MAPTMEN1KMT2ASYK
SCHEMBL27309337 0.83 ALDH1A1 (0.68) PLAUMAPTMEN1KMT2ACYP1A2
SCHEMBL7559758 0.82 MTNR1B (0.60) RAPGEF4ABCG2ABCB1MAPTABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096209-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-06-01 WO disclosed