SCHEMBL20067339

SCHEMBL20067339

COc1cccc(Nc2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
POLB P06746 3/20 0.60
TRPV1 Q8NER1 1/20 0.57
ABCG2 Q9UNQ0 4/20 0.57
ABCB1 P08183 3/20 0.57
MAPT P10636 2/20 0.57
MAPK1 P28482 1/20 0.57
ABCC1 P33527 1/20 0.57
TP53 P04637 1/20 0.57
PDE5A O76074 1/20 0.55
RAPGEF4 Q8WZA2 1/20 0.54
MTNR1A P48039 2/20 0.54
MTNR1B P49286 2/20 0.54
ADORA3 P0DMS8 1/20 0.54
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
NLRP3 Q96P20 1/20 0.51
LMNA P02545 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2541551 0.93 TRPV1 (0.57) MEN1KMT2APOLBTRPV1ABCG2
SCHEMBL7559758 0.91 MTNR1B (0.60) MEN1KMT2APOLBTRPV1ABCG2
SCHEMBL917608 0.89 MTNR1B (0.65) MEN1KMT2APOLBABCG2ABCB1
SCHEMBL30080139 0.89 MTNR1B (0.65) MEN1KMT2APOLBABCG2ABCB1
SCHEMBL9479511 0.87 MTNR1B (0.68) MEN1KMT2APOLBABCG2ABCB1
SCHEMBL9479608 0.87 MTNR1B (0.68) MEN1KMT2APOLBABCG2ABCB1
SCHEMBL25569175 0.87 PLAU (0.53) MEN1KMT2APOLBTRPV1ABCG2
SCHEMBL1085867 0.87 MEN1 (0.71) MEN1KMT2APOLBMAPTMAPK1
SCHEMBL1921418 0.85 MTNR1B (0.66) MEN1KMT2APOLBTRPV1MAPT
Nitrogen SCHEMBL2980327 0.85 MTNR1B (0.61) MEN1KMT2APOLBABCG2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021020873-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-02-04 WO disclosed
US-20180105534-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE NANJING TOPTO MATERIALS CO.,LTD. (CN) 2018-04-19 US disclosed
US-20180105534-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE NANJING TOPTO MATERIALS CO.,LTD. (CN) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180105534-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE PNMT, H1-0, H1-10 MEN1 2197/4885KMT2A 1030/4885POLB 1075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.