SCHEMBL25569409

SCHEMBL25569409

CC(C)(O[C@@H]1C(O)[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1CO)P(C)(=O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.58
▸ HINT1 P49773 4/20 0.56
▸ TGM2 P21980 1/20 0.55
▸ HPGD P15428 2/20 0.52
▸ TAS1R3 Q7RTX0 2/20 0.52
▸ TAS1R1 Q7RTX1 2/20 0.52
▸ KRAS P01116 4/20 0.52
▸ IMPDH2 P12268 3/20 0.51
▸ IMPDH1 P20839 1/20 0.51
▸ FUT5 Q11128 1/20 0.51
▸ GSK3A P49840 2/20 0.49
▸ RPS6KA3 P51812 2/20 0.49
▸ MAPK14 Q16539 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25569370 0.90 NT5E (0.61) NT5EHINT1TGM2TAS1R3TAS1R1
SCHEMBL25070741 0.89 HINT1 (0.59) NT5EHINT1TGM2HPGDTAS1R3
SCHEMBL94114 0.86 NT5E (0.64) NT5EHINT1TGM2HPGDTAS1R3
SCHEMBL1533806 0.86 NT5E (0.64) NT5EHINT1TGM2HPGDTAS1R3
SCHEMBL11327141 0.85 NT5E (0.63) NT5EHINT1TGM2HPGDTAS1R3
SCHEMBL1639395 0.85 HINT1 (0.61) NT5EHINT1TGM2HPGDTAS1R3
SCHEMBL23679991 0.85 HINT1 (0.61) NT5EHINT1TGM2HPGDTAS1R3
SCHEMBL22883381 0.85 HINT1 (0.61) NT5EHINT1TGM2HPGDTAS1R3
Guanosine SCHEMBL9238739 0.85 NT5E (0.69) NT5EHINT1TGM2HPGDKRAS
SCHEMBL20444711 0.85 HINT1 (0.61) NT5EHINT1TGM2HPGDTAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167152-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167152-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLI, POLL, DNMT3A NT5E 287/4885HINT1 1834/4885TGM2 2804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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