SCHEMBL25569370

SCHEMBL25569370

CC(C)(O[C@@H]1C(O)[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(O)C(C)(C)C)P(C)(=O)O

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.61
▸ TGM2 P21980 1/20 0.57
▸ KRAS P01116 10/20 0.56
▸ HINT1 P49773 1/20 0.55
▸ FUT5 Q11128 1/20 0.54
▸ TAS1R3 Q7RTX0 2/20 0.52
▸ TAS1R1 Q7RTX1 2/20 0.52
▸ IMPDH2 P12268 4/20 0.52
▸ IMPDH1 P20839 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25569409 0.90 NT5E (0.58) NT5ETGM2KRASHINT1FUT5
SCHEMBL25569380 0.85 P2RY1 (0.63) NT5ETAS1R3TAS1R1
SCHEMBL25070727 0.84 TGM2 (0.63) NT5ETGM2KRASHINT1FUT5
SCHEMBL25070718 0.83 TGM2 (0.65) NT5ETGM2KRASHINT1FUT5
SCHEMBL10037916 0.82 NT5E (0.68) NT5ETGM2KRASHINT1FUT5
SCHEMBL10067882 0.82 NT5E (0.68) NT5ETGM2KRASHINT1FUT5
SCHEMBL13638722 0.82 NT5E (0.68) NT5ETGM2KRASHINT1FUT5
SCHEMBL5828417 0.82 NT5E (0.68) NT5ETGM2KRASHINT1FUT5
SCHEMBL9976681 0.82 NT5E (0.68) NT5ETGM2KRASHINT1FUT5
SCHEMBL2315499 0.81 NT5E (0.69) NT5ETGM2KRASHINT1FUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312635-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-05 — — US disclosed
US-20230242570-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-03 — — US disclosed
US-20230167152-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312635-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLRMT, RNGTT, POLM NT5E 106/4885TGM2 4199/4885KRAS 1405/4885
US-20230167152-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLI, POLL, DNMT3A NT5E 287/4885TGM2 2804/4885KRAS 526/4885
US-20230242570-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER FBL, POLI, POLL NT5E 196/4885TGM2 2103/4885KRAS 2021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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