Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LPL | P06858 | 5/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29186351 | 1.00 | CYP2C9 (0.49) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL2554148 | 0.95 | CYP2C9 (0.48) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6558025 | 0.95 | CYP2C9 (0.48) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28639173 | 0.94 | LPL (0.47) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL13326212 | 0.94 | LPL (0.47) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL3025618 | 0.90 | CYP2C9 (0.59) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6556143 | 0.90 | CYP2C9 (0.59) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8113908 | 0.89 | CYP2C9 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8107212 | 0.89 | CYP2C9 (0.46) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11185308 | 0.87 | CYP2C9 (0.56) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595415-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2026-04-07 | — | — | US | disclosed |
| EP-4314194-B1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2025-09-10 | — | — | EP | disclosed |
| EP-4263751-B1 | HETEROAROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2025-08-13 | — | — | EP | disclosed |
| US-12359128-B2 | Heteroaromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2025-07-15 | — | — | US | disclosed |
| EP-4263750-B1 | HETEROAROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2025-06-04 | — | — | EP | disclosed |
| EP-4237508-B1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2025-04-30 | — | — | EP | disclosed |
| CN-116507695-B | Aromatic isothiocyanates | 默克专利股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-12203023-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2025-01-21 | — | — | US | disclosed |
| US-12077703-B2 | Heteroaromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2024-09-03 | — | — | US | disclosed |
| US-20240199957-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-06-20 | — | — | US | disclosed |
| WO-2022090099-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022090099-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| CN-113528148-A | Liquid crystal medium for high-frequency technology and assembly thereof | 西安近代化学研究所 | 2021-10-22 | — | — | CN | disclosed |
| CN-113528149-A | Liquid crystal compound, liquid crystal composition and high-frequency assembly comprising liquid crystal compound | 西安近代化学研究所 | 2021-10-22 | — | — | CN | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595415-B2 | Aromatic isothiocyanates | NAF1, H1-0, HNRNPU | CYP2C9 4228/4885ALDH1A1 1660/4885LMNA 900/4885 |
| US-12077703-B2 | Heteroaromatic isothiocyanates | TRPA1, CRY1, FOXM1 | CYP2C9 1178/4885ALDH1A1 1450/4885LMNA 2725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.