Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.35 |
| ▸ | CHRNG | P07510 | 3/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | CHRND | Q07001 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24197476 | 0.89 | HTR1B (0.45) | HTR1BHDAC1HDAC8HDAC6CHRNA1 | |
| SCHEMBL25569647 | 0.85 | MAPT (0.35) | HTR1BHDAC1HDAC8HDAC6CHRNA1 | |
| SCHEMBL7098217 | 0.82 | ALDH1A1 (0.40) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL25569656 | 0.82 | HDAC1 (0.34) | HTR1BHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL1865789 | 0.77 | MAPT (0.50) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL25569789 | 0.76 | MAPT (0.35) | HDAC1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL3142775 | 0.76 | ALDH1A1 (0.57) | KDM4EALDH1A1ALOX15CASP1CASP7 | |
| SCHEMBL25569655 | 0.76 | HDAC1 (0.34) | HDAC1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL7759522 | 0.75 | ALDH1A1 (0.52) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL10692438 | 0.74 | ALDH1A1 (0.39) | HDAC1HDAC8HDAC6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | TACTOGEN INC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | TACTOGEN INC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | SLC6A3, CREBBP, SLC1A2 | HTR1B 511/4885HDAC1 1235/4885HDAC8 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.