Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.43 |
| ▸ | WNT3A | P56704 | 3/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25569794 | 0.87 | OPRM1 (0.46) | CYP2A6OPRM1OPRK1CTNNB1WNT3A | |
| SCHEMBL3815862 | 0.83 | CYP2A6 (0.56) | CYP2A6OPRM1OPRK1CTNNB1WNT3A | |
| SCHEMBL631209 | 0.81 | CYP2A6 (0.58) | CYP2A6OPRM1OPRK1CTNNB1WNT3A | |
| SCHEMBL1774025 | 0.77 | CYP2A6 (0.66) | CYP2A6OPRM1OPRK1CTNNB1WNT3A | |
| SCHEMBL2494708 | 0.76 | CYP2A6 (0.56) | CYP2A6OPRM1OPRK1CTNNB1WNT3A | |
| SCHEMBL25569768 | 0.75 | OPRM1 (0.53) | CYP2A6OPRM1OPRK1CTNNB1WNT3A | |
| SCHEMBL11098549 | 0.74 | CYP2A6 (0.53) | CYP2A6OPRM1OPRK1CTNNB1WNT3A | |
| SCHEMBL3789042 | 0.74 | CYP2A6 (0.61) | CYP2A6OPRM1OPRK1CTNNB1WNT3A | |
| SCHEMBL6329466 | 0.73 | CTNNB1 (0.65) | CYP2A6CTNNB1WNT3ACA12CA2 | |
| SCHEMBL202744 | 0.73 | CYP2A6 (0.66) | CYP2A6OPRM1OPRK1CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | TACTOGEN INC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | TACTOGEN INC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | SLC6A3, CREBBP, SLC1A2 | CYP2A6 1879/4885OPRM1 1733/4885OPRK1 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.