Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.36 |
| ▸ | HTR3A | P46098 | 3/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25569772 | 0.87 | CYP2A6 (0.53) | OPRM1OPRK1MRGPRX4CYP2A6CTNNB1 | |
| SCHEMBL30211365 | 0.83 | OPRM1 (0.48) | OPRM1OPRK1MRGPRX4CYP2A6CHRNA7 | |
| SCHEMBL25569762 | 0.83 | OPRM1 (0.48) | OPRM1OPRK1MRGPRX4CYP2A6CHRNA7 | |
| SCHEMBL6544511 | 0.81 | PTGS1 (0.47) | OPRM1OPRK1MRGPRX4CYP2A6PTGS1 | |
| SCHEMBL154793 | 0.77 | CYP2A6 (0.47) | OPRM1OPRK1MRGPRX4CYP2A6AKR1C3 | |
| SCHEMBL6335648 | 0.77 | CTNNB1 (0.49) | MRGPRX4CHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL25569764 | 0.75 | OPRM1 (0.53) | OPRM1OPRK1MRGPRX4MAPK8MAPK10 | |
| SCHEMBL3799097 | 0.74 | CYP2A6 (0.43) | OPRM1OPRK1MRGPRX4CYP2A6 | |
| SCHEMBL3150204 | 0.73 | CYP2A6 (0.46) | OPRM1OPRK1MRGPRX4CYP2A6CHRNA7 | |
| SCHEMBL31621489 | 0.73 | MRGPRX4 (0.47) | MRGPRX4ALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | TACTOGEN INC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | TACTOGEN INC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159487-A1 | ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT | SLC6A3, CREBBP, SLC1A2 | OPRM1 1733/4885OPRK1 1113/4885MRGPRX4 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.