Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25570879 | 0.99 | ALDH1A1 (0.38) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570326 | 0.98 | CDK8 (0.38) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570595 | 0.98 | CDK8 (0.38) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570796 | 0.98 | MAPT (0.40) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570794 | 0.96 | ALDH1A1 (0.39) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570791 | 0.96 | ALDH1A1 (0.39) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570941 | 0.96 | ALDH1A1 (0.39) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570952 | 0.96 | ALDH1A1 (0.39) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570945 | 0.96 | ALDH1A1 (0.39) | MAPTALDH1A1CDK8CCNCGAA | |
| SCHEMBL25570390 | 0.95 | NPC1 (0.38) | MAPTALDH1A1CDK8CCNCGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167097-A1 | HETEROCYCLIC COMPOUND HAVING CYANO-SUBSTITUTION | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167097-A1 | HETEROCYCLIC COMPOUND HAVING CYANO-SUBSTITUTION | KCNH1, MCM4, MCM2 | MAPT 4257/4885ALDH1A1 1370/4885CDK8 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.