Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787490 | 0.96 | LMNA (0.50) | LMNAALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL17787483 | 0.93 | LMNA (0.49) | LMNAALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL17787474 | 0.91 | LMNA (0.50) | LMNAALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL25760984 | 0.82 | LMNA (0.52) | LMNAALDH1A1MAPK1L3MBTL1GAA | |
| SCHEMBL6501989 | 0.81 | ALDH1A1 (0.57) | LMNAALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL25575713 | 0.80 | ALDH1A1 (0.53) | LMNAALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL13702211 | 0.79 | ALDH1A1 (0.62) | LMNAALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL20224993 | 0.79 | LMNA (0.62) | LMNAALDH1A1MAPK1L3MBTL1GAA | |
| SCHEMBL13901148 | 0.79 | ALDH1A1 (0.54) | LMNAALDH1A1MAPK1L3MBTL1EPHX2 | |
| SCHEMBL27086436 | 0.78 | LMNA (0.47) | LMNAALDH1A1MAPK1L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183773-A1 | ZWITTERIONIC REAGENTS | Siemens Healthcare Diagnostics Inc. (US) | 2023-05-24 | — | — | EP | disclosed |