SCHEMBL25576166

SCHEMBL25576166

Clc1ccc(-c2ccc3c(c2)-c2cccc4c2C3(c2ccccc2)c2ccccc2N4)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
PDK2 Q15119 3/20 0.39
PGR P06401 4/20 0.36
CYP1A2 P05177 1/20 0.36
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
JAK2 O60674 1/20 0.34
NTRK1 P04629 1/20 0.34
MET P08581 1/20 0.34
FGFR1 P11362 1/20 0.34
PRKACA P17612 1/20 0.34
KDR P35968 1/20 0.34
MAP2K2 P36507 1/20 0.34
FLT3 P36888 1/20 0.34
GSK3B P49841 1/20 0.34
MAP2K1 Q02750 1/20 0.34
MST1R Q04912 1/20 0.34
NTRK3 Q16288 1/20 0.34
NTRK2 Q16620 1/20 0.34
CAMK1D Q8IU85 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25576170 0.90 PDK2 (0.48) LMNAPDK2PGRCYP1A2CHEK1
SCHEMBL16858256 0.84 PDK2 (0.49) LMNAPDK2CYP1A2EDNRBEDNRA
SCHEMBL25815231 0.84 PDK2 (0.49) LMNAPDK2CYP1A2EDNRBEDNRA
SCHEMBL25858527 0.84 PDK2 (0.49) LMNAPDK2CYP1A2EDNRBEDNRA
SCHEMBL25815261 0.83 PDK2 (0.46) LMNAPDK2CYP1A2EDNRBEDNRA
SCHEMBL22151044 0.82 MEN1 (0.49) LMNAPDK2CYP1A2EDNRBEDNRA
SCHEMBL25576154 0.81 LMNA (0.45) LMNAPDK2PGRCHEK1MAPT
SCHEMBL5581522 0.80 LMNA (0.50) LMNAPDK2PGRFLT3KDM4E
SCHEMBL5582092 0.78 LMNA (0.51) LMNAPDK2PGRFLT3KDM4E
SCHEMBL25124913 0.78 PDK2 (0.54) LMNAPDK2CYP1A2EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165137-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230165137-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165137-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SLC1A2, SLC18A1, SLC18A2 LMNA 1352/4885PDK2 1385/4885PGR 2986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.