Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FER | P16591 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5581522 | 0.98 | LMNA (0.50) | LMNACHRM2ADORA3KCNH2FLT3 | |
| SCHEMBL28164935 | 0.92 | LMNA (0.45) | LMNACHRM2ADORA3KCNH2FLT3 | |
| SCHEMBL5582199 | 0.90 | LMNA (0.43) | LMNACHRM2ADORA3KCNH2FLT3 | |
| SCHEMBL28310002 | 0.89 | LMNA (0.49) | LMNACHRM2ADORA3KCNH2MEN1 | |
| SCHEMBL22719989 | 0.89 | LMNA (0.42) | LMNACHRM2ADORA3KCNH2FLT3 | |
| SCHEMBL29373003 | 0.79 | LMNA (0.69) | LMNACHRM2ADORA3KCNH2MEN1 | |
| SCHEMBL2453350 | 0.79 | LMNA (0.69) | LMNACHRM2ADORA3KCNH2MEN1 | |
| SCHEMBL30259105 | 0.79 | LMNA (0.44) | LMNACHRM2ADORA3KCNH2MEN1 | |
| SCHEMBL25576166 | 0.78 | LMNA (0.41) | LMNAFLT3MEN1MAPTKMT2A | |
| SCHEMBL25576170 | 0.78 | PDK2 (0.48) | LMNAPGRPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840120-B1 | N-Heterocyclic compounds and their use in electronic, optoelectronic and electroluminiscent components | NOVALED AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-1840120-A1 | N-Heterocyclic compounds and their use in electronic, optoelectronic and electroluminiscent components | Novaled AG (DE) | 2007-10-03 | — | — | EP | disclosed |