Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028540 | 1.00 | CRBN (0.57) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30703123 | 1.00 | CRBN (0.57) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL1264462 | 0.90 | OPRM1 (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30998388 | 0.90 | OPRM1 (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL1265932 | 0.90 | OPRM1 (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL2557414 | 0.84 | CRBN (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL1265365 | 0.83 | CRBN (0.57) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30998375 | 0.83 | CRBN (0.57) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL1265364 | 0.83 | CRBN (0.57) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL14602355 | 0.82 | OPRM1 (0.49) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024013209-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-01-18 | — | — | WO | disclosed |
| US-9701633-B2 | Methods and intermediates useful for the preparation of alpha-branched aryl phthalimides and alpha-branched aryl amines | Ripon College (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701633-B2 | Methods and intermediates useful for the preparation of alpha-branched aryl phthalimides and alpha-branched aryl amines | Ripon College (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160200680-A1 | Methods and Intermediates Useful for the Preparation of alpha-Branched Aryl Phthalimides and alpha-Branched Aryl Amines | Ripon College | 2016-07-14 | — | — | US | disclosed |
| US-20160200680-A1 | Methods and Intermediates Useful for the Preparation of alpha-Branched Aryl Phthalimides and alpha-Branched Aryl Amines | Ripon College | 2016-07-14 | — | — | US | disclosed |
| WO-2011121062-A1 | COMPOSITION FOR THE TREATMENT OF PERIODONTITIS AND OTHER INFLAMMATORY INFECTIOUS DISEASES | VOCKNER HELMUT (AT) | 2011-10-06 | — | — | WO | disclosed |
| US-7893071-B2 | Substituted phthalimide and isoquinoline derivatives; thalidomide analogs that lack the piperidine-2,6-dione moiety of thalidomide | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-02-22 | — | — | US | disclosed |
| US-7893071-B2 | Substituted phthalimide and isoquinoline derivatives; thalidomide analogs that lack the piperidine-2,6-dione moiety of thalidomide | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200680-A1 | Methods and Intermediates Useful for the Preparation of alpha-Branched Aryl Phthalimides and alpha-Branched Aryl Amines | PAH, BCAT1, BCAT2 | CRBN 188/4885DDB1 913/4885IKZF3 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.