Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331882 | 0.88 | ALDH1A1 (0.60) | ALDH1A1TDP1KDM4ETSHRHPGD | |
| SCHEMBL15330401 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1KDM4EHPGDSIGMAR1 | |
| SCHEMBL29952645 | 0.84 | SIGMAR1 (0.43) | ALDH1A1TDP1KDM4EHPGDSIGMAR1 | |
| SCHEMBL27711029 | 0.83 | HPGD (0.43) | ALDH1A1TDP1KDM4EHPGDSIGMAR1 | |
| SCHEMBL2560060 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TDP1KDM4EPOLBTSHR | |
| SCHEMBL2560224 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1KDM4ETSHRHPGD | |
| SCHEMBL2554840 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRHPGDSIGMAR1 | |
| SCHEMBL2555776 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TDP1POLBTSHRSIGMAR1 | |
| SCHEMBL2557667 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1KDM4EHPGDKMT2A | |
| SCHEMBL2556555 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4ETSHRHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |