Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330401 | 0.92 | ALDH1A1 (0.45) | SIGMAR1ALDH1A1OPRD1HPGDBCHE | |
| SCHEMBL27711029 | 0.86 | HPGD (0.43) | SIGMAR1ALDH1A1HPGDBCHETDP1 | |
| SCHEMBL2560060 | 0.86 | ALDH1A1 (0.51) | SIGMAR1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL2560224 | 0.85 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL2554840 | 0.84 | ALDH1A1 (0.43) | SIGMAR1ALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL2557727 | 0.84 | ALDH1A1 (0.45) | SIGMAR1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL29955822 | 0.83 | SIGMAR1 (0.44) | SIGMAR1ALDH1A1OPRD1HPGDTDP1 | |
| SCHEMBL2555776 | 0.83 | ALDH1A1 (0.43) | SIGMAR1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL15331882 | 0.83 | ALDH1A1 (0.60) | SIGMAR1ALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL2560295 | 0.82 | L3MBTL1 (0.45) | ALDH1A1HPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |