SCHEMBL2558034

SCHEMBL2558034

Cc1cccc(C(C=O)C=O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.46
ACP3 P15309 1/20 0.46
TSHR P16473 1/20 0.41
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AOC3 Q16853 1/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPK1 P28482 1/20 0.38
NPC1 O15118 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
HPGD P15428 1/20 0.37
PARP1 P09874 1/20 0.36
HSD17B2 P37059 1/20 0.36
GAA P10253 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9729373 0.83 ACHE (0.46) ACHEACP3TSHRTP53TDP1
SCHEMBL9870224 0.81 ACP3 (0.44) ACHEACP3TSHRTP53TDP1
SCHEMBL8718778 0.81 ACP3 (0.44) ACHEACP3TP53TDP1AOC3
SCHEMBL31490296 0.81 ACP3 (0.44) ACHEACP3TSHRTP53TDP1
SCHEMBL1712796 0.79 ACP3 (0.47) ACHEACP3TP53TDP1AOC3
SCHEMBL4960285 0.79 ACP3 (0.43) ACHEACP3TSHRTP53TDP1
SCHEMBL27886187 0.78 TP53 (0.48) ACHEACP3TP53TDP1AOC3
SCHEMBL1515743 0.78 ACP3 (0.50) ACHEACP3TSHRAOC3MAPK1
SCHEMBL22867716 0.76 ACP3 (0.41) ACHEACP3TP53TDP1AOC3
SCHEMBL31347981 0.76 ACP3 (0.41) ACHEACP3TP53TDP1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321523-B Preparation method and application of oxazolone compound capable of inhibiting bacteria in patient care process 河南科技大学第一附属医院 2021-04-30 CN claimed
CN-112321523-A Preparation method and application of oxazolone compound capable of inhibiting bacteria in patient care process 河南科技大学第一附属医院 2021-02-05 CN claimed
CN-111559985-A Oxazolone compound with bactericidal effect and preparation method thereof 河南科技大学第一附属医院 2020-08-21 CN claimed
CN-109666163-B Hybrid crosslinked dynamic polymer and application thereof 厦门逍扬运动科技有限公司 2023-05-12 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
CN-112321523-B Preparation method and application of oxazolone compound capable of inhibiting bacteria in patient care process 河南科技大学第一附属医院 2021-04-30 CN disclosed
CN-112321523-A Preparation method and application of oxazolone compound capable of inhibiting bacteria in patient care process 河南科技大学第一附属医院 2021-02-05 CN disclosed
CN-111559985-A Oxazolone compound with bactericidal effect and preparation method thereof 河南科技大学第一附属医院 2020-08-21 CN disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed