Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960285 | 0.82 | ACP3 (0.43) | ACP3ACHEALDH1A1MAPK1AOC3 | |
| SCHEMBL9729373 | 0.81 | ACHE (0.46) | ACP3ACHEALDH1A1MAPK1AOC3 | |
| SCHEMBL2558034 | 0.81 | ACHE (0.46) | ACP3ACHEALDH1A1MAPK1AOC3 | |
| SCHEMBL9870224 | 0.79 | ACP3 (0.44) | ACP3ACHEALDH1A1MAPK1AOC3 | |
| SCHEMBL31490296 | 0.79 | ACP3 (0.44) | ACP3ACHEALDH1A1MAPK1AOC3 | |
| SCHEMBL1712796 | 0.78 | ACP3 (0.47) | ACP3ACHEAOC3TP53TDP1 | |
| SCHEMBL27605513 | 0.77 | ACP3 (0.40) | ACP3ACHEALDH1A1MAPK1AOC3 | |
| SCHEMBL1515743 | 0.76 | ACP3 (0.50) | ACP3ACHEMAPK1AOC3LMNA | |
| SCHEMBL7352298 | 0.76 | ACHE (0.50) | ACP3ACHEALDH1A1MAPK1AOC3 | |
| SCHEMBL22867716 | 0.75 | ACP3 (0.41) | ACP3ACHEALDH1A1AOC3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722448-A4 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO INC (US) | 1998-04-29 | — | — | EP | claimed |
| EP-0722448-A1 | O-ARYL, O-ALKYL, O-ALKENYL AND O-ALKYNYL-MACROLIDES HAVING IMMUNOSUPPRESSIVE ACTIVITY | MERCK & CO. INC. (US) | 1996-07-24 | — | — | EP | claimed |