Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13585083 | 0.80 | TYR (0.48) | TP53TDP1PTGS1HDAC8 | |
| SCHEMBL6752527 | 0.80 | TP53 (0.55) | ACP3TP53TDP1ACHEHSD17B2 | |
| SCHEMBL2558034 | 0.79 | ACHE (0.46) | ACP3TP53TDP1ACHEHSD17B2 | |
| SCHEMBL9729373 | 0.79 | ACHE (0.46) | ACP3TP53TDP1ACHEHSD17B2 | |
| SCHEMBL13628507 | 0.78 | ADRB1 (0.48) | LMNAHSD17B10 | |
| SCHEMBL8718778 | 0.78 | ACP3 (0.44) | ACP3TP53TDP1ACHEHSD17B2 | |
| SCHEMBL31490296 | 0.78 | ACP3 (0.44) | ACP3TP53TDP1ACHEHSD17B2 | |
| SCHEMBL9870224 | 0.78 | ACP3 (0.44) | ACP3TP53TDP1ACHEHSD17B2 | |
| SCHEMBL6035448 | 0.76 | ACHE (0.52) | ACP3TP53TDP1ACHEHSD17B2 | |
| SCHEMBL822105 | 0.76 | ACHE (0.52) | ACP3TP53TDP1ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344460-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Galapagos N.V. (BE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010029119-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | GALAPAGOS NV (BE) | 2010-03-18 | — | — | WO | disclosed |