SCHEMBL25580607

SCHEMBL25580607

Cc1c(Cl)cc(N2C(=O)C=CC2=O)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR6 P51684 5/20 0.59
HSP90AA1 P07900 4/20 0.59
MGLL Q99685 11/20 0.48
FAAH O00519 2/20 0.46
G6PD P11413 2/20 0.44
NSD2 O96028 1/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
HPGD P15428 2/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
PKM P14618 2/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11666213 0.78 MGLL (0.48) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL25586084 0.78 MGLL (0.48) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL8005849 0.78 PKM (0.58) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL19067090 0.78 CCR6 (0.50) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL30198527 0.78 PKM (0.58) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL3171879 0.77 MGLL (0.62) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL5078820 0.77 MGLL (0.62) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL8641616 0.75 MGLL (0.70) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL3483046 0.75 HSP90AA1 (1.00) CCR6HSP90AA1MGLLFAAHG6PD
SCHEMBL144792 0.75 HSP90AA1 (0.91) CCR6HSP90AA1MGLLFAAHG6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158141-A1 Conjugates of Biomolecule and Use Thereof YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOG (CN) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158141-A1 Conjugates of Biomolecule and Use Thereof CD47, FCGR2A, CD40 CCR6 368/4885HSP90AA1 1851/4885MGLL 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.