SCHEMBL8005849

SCHEMBL8005849

Cc1ccc(N2C(=O)C=CC2=O)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 2/20 0.58
▸ ALDH1A1 P00352 4/20 0.55
▸ HPGD P15428 4/20 0.55
▸ SMN1; SMN2 Q16637 2/20 0.55
▸ MAPT P10636 4/20 0.54
▸ HSP90AA1 P07900 4/20 0.54
▸ NPSR1 Q6W5P4 3/20 0.54
▸ L3MBTL1 Q9Y468 2/20 0.54
▸ CCR6 P51684 2/20 0.54
▸ G6PD P11413 2/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ MCL1 Q07820 1/20 0.54
▸ MGLL Q99685 7/20 0.53
▸ FAAH O00519 2/20 0.52
▸ HTT P42858 2/20 0.51
▸ LMNA P02545 1/20 0.51
▸ USP2 O75604 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49
▸ MITF O75030 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30198527 1.00 PKM (0.58) PKMALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL30435094 0.82 MGLL (0.59) PKMALDH1A1HPGDMAPTHSP90AA1
SCHEMBL1164427 0.82 MGLL (0.59) PKMALDH1A1HPGDMAPTHSP90AA1
SCHEMBL2345040 0.82 MAPT (0.61) PKMALDH1A1HPGDMAPTHSP90AA1
SCHEMBL9876149 0.81 MAPT (0.60) PKMALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL11611638 0.81 MAPT (0.64) PKMALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL10587456 0.78 MGLL (0.57) PKMALDH1A1HPGDMAPTHSP90AA1
SCHEMBL94095 0.78 MGLL (0.57) PKMHSP90AA1NPSR1CCR6G6PD
SCHEMBL25580607 0.78 CCR6 (0.59) PKMALDH1A1HPGDMAPTHSP90AA1
SCHEMBL15758697 0.77 MGLL (0.59) ALDH1A1HPGDMAPTHSP90AA1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4525864-A2 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO Emory University (US) 2025-03-26 — — EP claimed
WO-2023225300-A2 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO EMORY UNIVERSITY (US) 2023-11-23 — — WO claimed
CN-115591418-B Diaphragm for trapping dioxin and preparation method thereof 佛山(华南)新材料研究院 2023-06-09 — — CN claimed
CN-115591418-A Membrane for trapping dioxin and preparation method thereof 佛山(华南)新材料研究院(CN) 2023-01-13 — — CN claimed
EP-4061961-B1 METHOD FOR DOUBLE STRAND SEQUENCING OXFORD NANOPORE TECH PLC (GB) 2026-04-08 — — EP disclosed
US-20260072009-A1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-12 — — US disclosed
US-20260072008-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE UNIV OXFORD INNOVATION LTD (GB) 2026-03-12 — — US disclosed
US-20260063618-A1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE Oxford Nanopore Technolgies PLC (GB) 2026-03-05 — — US disclosed
EP-4270008-B1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE OXFORD NANOPORE TECH PLC (GB) 2026-02-04 — — EP disclosed
EP-4127711-B1 METHOD OF DETECTING AN ANALYTE IN A MEDIUM COMPRISING A LIGHT SCATTERING CONSTITUENT KING S COLLEGE LONDON (GB) 2025-12-24 — — EP disclosed
EP-4662489-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE Oxford University Innovation Limited (GB) 2025-12-17 — — EP disclosed
US-20250361243-A1 Compounds and Pharmaceutical Compositions Useful for Managing Sickle Cell Disease and Conditions Related Thereto UNIV EMORY (US) 2025-11-27 — — US disclosed
WO-2021111139-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-06-10 — — WO disclosed
WO-2021099801-A1 METHOD FOR DOUBLE STRAND SEQUENCING OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-05-27 — — WO disclosed
CN-112189054-A Method of producing a composite material 牛津纳米孔科技公司 2021-01-05 — — CN disclosed
US-20130025495-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF ISP INVESTMENTS INC. (US) 2013-01-31 — — US disclosed
US-20130025495-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF ISP INVESTMENTS INC. (US) 2013-01-31 — — US disclosed
US-20130025495-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF ISP INVESTMENTS INC. (US) 2013-01-31 — — US disclosed
US-6153645-A FOR INHIBITING GROWTH OF MICROORGANISMS; INHIBITOR OF AMINOACYL-TRNA SYNTHETASE CUBIST PHARMACEUTICALS, INC. (US) 2000-11-28 — — US disclosed
WO-2000017206-A1 TETRACYCLIC HETEROCYCLES AS ANTIMICROBIAL AGENTS CUBIST PHARMACEUTICALS, INC. (US) 2000-03-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260072008-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE MAX, NPPA, NUP210 PKM 2308/4885ALDH1A1 4882/4885HPGD 4643/4885
US-20130025495-A1 COMPOSITIONS COMPRISING A REACTIVE MONOMER AND USES THEREOF MEP1A, MACF1, CYP1B1 PKM 1982/4885ALDH1A1 34/4885HPGD 694/4885
US-20260063618-A1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE NUP210, NPPA, NUP160 PKM 2622/4885ALDH1A1 4884/4885HPGD 4738/4885
US-20250361243-A1 Compounds and Pharmaceutical Compositions Useful for Managing Sickle Cell Disease and Conditions Related Thereto THPO, HBG1, HBG2 PKM 210/4885ALDH1A1 84/4885HPGD 456/4885
US-20260072009-A1 METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE NUP210, SLC9A2, SLC9A3 PKM 3231/4885ALDH1A1 4883/4885HPGD 4742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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