Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13212863 | 0.79 | HRH3 (0.38) | HRH3KCNH2 | |
| SCHEMBL26203701 | 0.76 | HRH3 (0.37) | HRH3KCNH2 | |
| SCHEMBL24671069 | 0.72 | HRH3 (0.37) | HRH3KCNH2 | |
| SCHEMBL20348267 | 0.72 | HRH3 (0.40) | HRH3KCNH2 | |
| SCHEMBL14725147 | 0.72 | HRH3 (0.41) | HRH3KCNH2 | |
| SCHEMBL1261174 | 0.72 | HRH3 (0.44) | HRH3KCNH2 | |
| SCHEMBL25513773 | 0.71 | PIK3CA (0.38) | HRH3KCNH2 | |
| SCHEMBL17679889 | 0.71 | HRH3 (0.39) | HRH3KCNH2 | |
| SCHEMBL10104075 | 0.71 | HRH3 (0.41) | HRH3KCNH2 | |
| Hydrochloric Acid SCHEMBL2942000 | 0.70 | HRH3 (0.43) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | PADI4, PADI2, PADI6 | HRH3 1991/4885KCNH2 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.