Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 15/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 13/20 | 0.49 |
| ▸ | TSHR | P16473 | 12/20 | 0.49 |
| ▸ | USP2 | O75604 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273296 | 0.82 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL23981519 | 0.82 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL30397014 | 0.82 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL23981521 | 0.80 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL30396968 | 0.77 | PDE4B (0.47) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL25254910 | 0.77 | PDE4B (0.47) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL23981856 | 0.76 | PDE4B (0.47) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL30367939 | 0.76 | PDE4B (0.47) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL30396601 | 0.76 | PDE4B (0.47) | CYP1A2CYP3A4CYP2C19TSHRUSP2 | |
| SCHEMBL16343595 | 0.75 | MAPT (0.56) | CYP1A2CYP3A4CYP2C19TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174484-A1 | ANTAGONISTS OF GPR39 PROTEIN | UNIV OREGON HEALTH & SCIENCE (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174484-A1 | ANTAGONISTS OF GPR39 PROTEIN | GPR39, GPR139, GPR119 | CYP1A2 3826/4885CYP3A4 3711/4885CYP2C19 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.