Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301780 | 0.79 | CRHR1 (0.38) | ALDH1A1LMNAL3MBTL1MAPTMAP3K12 | |
| SCHEMBL24006492 | 0.76 | GRM2 (0.41) | GRM2ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL23566750 | 0.75 | CRHR1 (0.40) | GRM2KCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL20283020 | 0.75 | CNR1 (0.33) | GRM2KCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL3023672 | 0.73 | CRHR1 (0.43) | GRM2ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL21768453 | 0.72 | GRM2 (0.46) | GRM2CNR2 | |
| SCHEMBL17673143 | 0.69 | MPO (0.34) | LMNA | |
| SCHEMBL24758365 | 0.67 | P2RY14 (0.42) | KCNJ6KCNJ5KCNJ3LMNAMAPT | |
| SCHEMBL25213569 | 0.67 | SLC2A1 (0.36) | GRM2CNR1CNR2 | |
| SCHEMBL17045533 | 0.67 | MAP3K12 (0.38) | LMNAMAPTMAP3K12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096928-A1 | HETERO-ATOM CONTAINING COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-06-01 | — | — | WO | disclosed |