Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | APEX1 | P27695 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 13/20 | 0.59 |
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559881 | 1.00 | ESR1 (0.63) | ESR1TP53POLBAPEX1MAPK1 | |
| SCHEMBL15330025 | 0.84 | L3MBTL1 (0.65) | ESR1TP53POLBAPEX1MAPK1 | |
| SCHEMBL6816018 | 0.82 | TP53 (0.65) | ESR1TP53POLBAPEX1MAPK1 | |
| SCHEMBL2560777 | 0.80 | TP53 (0.60) | TP53MAOBMAOANR4A2NR4A1 | |
| SCHEMBL2559247 | 0.80 | TDP1 (0.60) | ESR1TP53POLBAPEX1MAPK1 | |
| SCHEMBL2087954 | 0.77 | MAOB (0.71) | MAOBMAOANR4A2NPC1RAB9A | |
| SCHEMBL2558882 | 0.75 | MAOB (0.60) | MAOBMAOANR4A2NR4A1NR4A3 | |
| SCHEMBL29954816 | 0.75 | MAOB (0.60) | MAOBMAOANR4A2NR4A1NR4A3 | |
| SCHEMBL68983 | 0.75 | MAOB (1.00) | MAOBMAOANR4A2KMT2A | |
| SCHEMBL21483757 | 0.74 | MAOB (0.67) | MAOBMAOANR4A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |