Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PDE2A | O00408 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590741 | 0.72 | KDM4E (0.37) | HSD17B10MAPTHPGDMEN1KMT2A | |
| SCHEMBL13901524 | 0.65 | KDM4E (0.38) | HSD17B10MAPTPOLBHPGDMEN1 | |
| SCHEMBL23508151 | 0.64 | HSP90AB1 (0.32) | — | |
| SCHEMBL11605145 | 0.63 | KDM4E (0.57) | HSD17B10MAPTPOLBHPGDMEN1 | |
| SCHEMBL14194710 | 0.62 | LRRK2 (0.32) | CYP1A2 | |
| SCHEMBL15550558 | 0.62 | PDE10A (0.50) | CYP1A2HTT | |
| SCHEMBL1007301 | 0.62 | KDM4E (0.56) | HSD17B10MAPTPOLBHPGDMEN1 | |
| SCHEMBL24582690 | 0.61 | HPGD (0.44) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL25096433 | 0.61 | GRM5 (0.41) | HSD17B10HPGDKDM4EHTTTSHR | |
| SCHEMBL20542245 | 0.61 | LMNA (0.41) | MAPTPOLBPDE2AHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186895-A1 | COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF | TYK Medicines Inc. (CN) | 2023-05-31 | — | — | EP | disclosed |