Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25591776 | 0.88 | ABL1 (0.50) | TRPV1TDO2MAPTNPC1SMN1; SMN2 | |
| SCHEMBL25593788 | 0.88 | ATR (0.48) | TDO2NPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL25593238 | 0.81 | ABL1 (0.47) | KDRTRPV1MAPTNPC1EGFR | |
| SCHEMBL25590564 | 0.81 | ROCK1 (0.48) | TRPV1MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL25590566 | 0.79 | NPC1 (0.49) | TRPV1MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL25590396 | 0.78 | CSF1R (0.53) | TRPV1MAPTNPC1NR3C1SMN1; SMN2 | |
| SCHEMBL25591687 | 0.77 | MAPT (0.62) | TRPV1MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL25590680 | 0.76 | MAPT (0.41) | KDRTRPV1MAPTNPC1NR3C1 | |
| SCHEMBL25590678 | 0.76 | MAOB (0.45) | KDRTRPV1MAPTNPC1NR3C1 | |
| SCHEMBL25590670 | 0.76 | ABL1 (0.47) | TDO2MAPTNPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |