Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590770 | 0.80 | MAPT (0.43) | MAPTNR3C1TRPV1AHRSMN1; SMN2 | |
| SCHEMBL25590678 | 0.79 | MAOB (0.45) | MAPTNR3C1TRPV1SMN1; SMN2MCHR1 | |
| SCHEMBL25590396 | 0.79 | CSF1R (0.53) | MAPTNR3C1TRPV1SMN1; SMN2MCHR1 | |
| SCHEMBL25593238 | 0.78 | ABL1 (0.47) | MAPTTRPV1AHRSMN1; SMN2KIT | |
| SCHEMBL25590686 | 0.77 | TRPV1 (0.46) | MAPTNR3C1TRPV1AHRKIT | |
| SCHEMBL25590768 | 0.76 | KDR (0.51) | MAPTNR3C1TRPV1SMN1; SMN2RXFP1 | |
| SCHEMBL25591687 | 0.76 | MAPT (0.62) | MAPTTRPV1LRRK2SMN1; SMN2MCHR1 | |
| SCHEMBL25590564 | 0.76 | ROCK1 (0.48) | MAPTTRPV1AHRLRRK2SMN1; SMN2 | |
| SCHEMBL25590566 | 0.76 | NPC1 (0.49) | MAPTTRPV1AHRSMN1; SMN2MCHR1 | |
| SCHEMBL25591484 | 0.76 | MAPT (0.46) | MAPTNR3C1TRPV1AHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |