Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH1C | P00326 | 2/20 | 0.39 |
| ▸ | ADH1A | P07327 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25466978 | 0.98 | FAAH (0.42) | ALDH1A1LMNAKMT2AFAAHADH1B | |
| SCHEMBL23945202 | 0.98 | FAAH (0.42) | ALDH1A1LMNAKMT2AFAAHADH1B | |
| SCHEMBL24935617 | 0.91 | ALDH1A1 (0.36) | ALDH1A1LMNAKMT2AFAAHADH1B | |
| SCHEMBL24607224 | 0.91 | EPHX2 (0.43) | ALDH1A1LMNAKMT2AFAAHADH1B | |
| SCHEMBL24608172 | 0.90 | EPHX2 (0.44) | ALDH1A1LMNAKMT2AFAAHADH1B | |
| SCHEMBL23945678 | 0.85 | KMT2A (0.41) | ALDH1A1LMNAKMT2AFAAHADH1B | |
| SCHEMBL25090249 | 0.84 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2AFAAHPOLB | |
| SCHEMBL23696371 | 0.82 | KMT2A (0.63) | ALDH1A1LMNAKMT2AFAAHMEN1 | |
| SCHEMBL22905020 | 0.82 | KDM4E (0.54) | ALDH1A1LMNAKMT2AFAAHMEN1 | |
| SCHEMBL14227461 | 0.82 | FAAH (0.59) | KMT2AFAAHMEN1EPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194457-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |