Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.61 |
| ▸ | DRD4 | P21917 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086976 | 0.96 | LMNA (0.67) | DRD2DRD4LMNAALDH1A1GAA | |
| SCHEMBL14640548 | 0.90 | DRD2 (0.59) | DRD2DRD4LMNAALDH1A1 | |
| SCHEMBL25590714 | 0.87 | LMNA (0.66) | DRD2DRD4LMNAALDH1A1GAA | |
| SCHEMBL10223337 | 0.82 | LMNA (0.72) | DRD2DRD4LMNAALDH1A1GAA | |
| SCHEMBL17717742 | 0.81 | DRD4 (0.55) | DRD2DRD4LMNAALDH1A1GAA | |
| SCHEMBL18850983 | 0.79 | GAA (0.59) | DRD2DRD4LMNAALDH1A1GAA | |
| SCHEMBL20243887 | 0.78 | DRD2 (0.60) | DRD2DRD4LMNAALDH1A1 | |
| SCHEMBL13450761 | 0.78 | EPHX1 (0.50) | DRD2DRD4ALDH1A1KDM4EMAPK1 | |
| SCHEMBL13915560 | 0.77 | LMNA (0.65) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL173141 | 0.77 | LMNA (0.57) | DRD2DRD4LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174538-A1 | Tricyclic heterocycles | MERCK PATENT GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174538-A1 | Tricyclic heterocycles | YAP1, TEAD1, TERF2IP | DRD2 4638/4885DRD4 4697/4885LMNA 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.