SCHEMBL25596188

SCHEMBL25596188

COc1ccc(CCC(C)(CF)C(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.47
FFAR1 O14842 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
PPARA Q07869 2/20 0.45
PPARD Q03181 1/20 0.45
LDHA P00338 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ALOX5 P09917 1/20 0.43
CALM1 P0DP23 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10644144 0.86 PPARA (0.50) F2RL1FFAR1SMN1; SMN2PPARAPPARD
SCHEMBL25596239 0.83 BLM (0.47)
SCHEMBL22033168 0.81 F2RL1 (0.46) F2RL1FFAR1SMN1; SMN2PPARAPPARD
SCHEMBL28136422 0.77 LDHA (0.53) F2RL1SMN1; SMN2PPARAPPARDLDHA
SCHEMBL25045888 0.75 PPARA (0.59) F2RL1FFAR1PPARAALOX5CALM1
SCHEMBL1236959 0.75 CALM1 (0.53) F2RL1FFAR1SMN1; SMN2PPARAALOX5
SCHEMBL18065719 0.75 NPC1 (0.58) F2RL1NPC1RAB9AALOX5
SCHEMBL11203493 0.75 FFAR1 (0.51) F2RL1FFAR1SMN1; SMN2LDHANPC1
SCHEMBL28184932 0.74 F2RL1 (0.53) F2RL1FFAR1SMN1; SMN2RAB9AALOX5
SCHEMBL10642941 0.74 CYP19A1 (0.54) SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230181493-A1 BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME SENDA BIOSCIENCES INC (US) 2023-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230181493-A1 BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME COMT, SNCA, PARK7 F2RL1 2433/4885FFAR1 4644/4885SMN1; SMN2 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.