Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25581942 | 0.85 | CHRNA7 (0.41) | BLMCYP2C9HSD17B10ESRRG | |
| SCHEMBL24253161 | 0.81 | BLM (0.40) | BLMHSD17B1ESR2ESR1RXRA | |
| SCHEMBL22074721 | 0.78 | BLM (0.58) | BLMHSD17B1ESR2ESR1RXRA | |
| SCHEMBL20991308 | 0.75 | ESR1 (0.48) | HSD17B1ESR2ESR1CYP2C9HSD17B10 | |
| SCHEMBL25596379 | 0.72 | ESR2 (0.41) | BLMESR2ESR1CYP2C9HSD17B10 | |
| SCHEMBL3927390 | 0.71 | CNR1 (0.38) | HSD17B1ESR2ESR1ESRRBESRRG | |
| SCHEMBL18179322 | 0.70 | ESR2 (0.46) | HSD17B1ESR2ESR1NR3C1PGR | |
| SCHEMBL27761921 | 0.70 | HSD17B1 (0.36) | BLMHSD17B1ESR2ESR1ESRRB | |
| SCHEMBL2587955 | 0.70 | RXRA (0.53) | RXRARXRBCYP2C9RXRGLMNA | |
| SCHEMBL3242324 | 0.69 | ESR1 (0.56) | ESR2ESR1HSD17B10ESRRGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181493-A1 | BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME | SENDA BIOSCIENCES INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181493-A1 | BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME | COMT, SNCA, PARK7 | BLM 3756/4885HSD17B1 3924/4885ESR2 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.