Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424931 | 0.86 | KDM4E (0.75) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL255577 | 0.79 | KDM4E (0.66) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL30803985 | 0.79 | KDM4E (0.66) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL12278703 | 0.79 | KDM4E (0.66) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL16847023 | 0.78 | ALDH1A1 (0.52) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL170969 | 0.78 | KDM4E (1.00) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| Bromide SCHEMBL162182 | 0.78 | KDM4E (0.64) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL970073 | 0.78 | KDM4E (0.64) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL174599 | 0.78 | KDM4E (0.64) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL30396089 | 0.78 | KDM4E (0.64) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |