Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554143 | 0.92 | SLC34A1 (0.43) | SLC34A1HPGDLMNAP2RX7PTGS2 | |
| SCHEMBL2564655 | 0.85 | PPARA (0.46) | SLC34A1LMNAP2RX7PTGS2NR3C1 | |
| SCHEMBL2561878 | 0.84 | PDE4D (0.41) | SLC34A1LMNAP2RX7PTGS2ALDH1A1 | |
| SCHEMBL2560863 | 0.82 | ALDH1A1 (0.55) | SLC34A1HPGDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12265091 | 0.77 | PDE4D (0.58) | SLC34A1HPGDLMNAPTGS2KDM4E | |
| SCHEMBL14553207 | 0.73 | PDE4D (0.50) | SLC34A1HPGDLMNAPTGS2KDM4E | |
| SCHEMBL2555825 | 0.72 | PDE4D (0.63) | HPGDLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL16500084 | 0.72 | TSHR (0.43) | HPGDLMNAP2RX7PTGS2HTT | |
| SCHEMBL2857382 | 0.72 | LMNA (0.53) | SLC34A1LMNAPTGS2CYP1A2CYP2C9 | |
| SCHEMBL20075443 | 0.72 | LMNA (0.52) | SLC34A1LMNAARCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552895-B1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | Westfälische Wilhelms Universität Münster (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2552895-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | Westfälische Wilhelms-Universität Münster (DE) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120861-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | WESTFÄLISHE WILHELMS-UNIVERSITÄT MÜNSTER (DE) | 2011-10-06 | — | — | WO | disclosed |