Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559798 | 0.85 | SLC34A1 (0.49) | P2RX7PTGS2SLC34A1NR3C1ALDH1A1 | |
| SCHEMBL2561878 | 0.81 | PDE4D (0.41) | P2RX7PTGS2SLC34A1ALDH1A1L3MBTL1 | |
| SCHEMBL2554143 | 0.81 | SLC34A1 (0.43) | P2RX7PTGS2SLC34A1NR3C1LMNA | |
| SCHEMBL12264385 | 0.81 | PPARA (0.47) | PPARAP2RX7PTGS2SLC34A1ALDH1A1 | |
| SCHEMBL2560863 | 0.79 | ALDH1A1 (0.55) | SLC34A1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14482134 | 0.76 | PPARA (0.56) | PPARAP2RX7PTGS2ALDH1A1POLB | |
| SCHEMBL28497651 | 0.75 | CFTR (0.45) | PPARAP2RX7MEN1KMT2ACFTR | |
| SCHEMBL16500084 | 0.69 | TSHR (0.43) | P2RX7PTGS2ALDH1A1POLBMEN1 | |
| SCHEMBL12265091 | 0.69 | PDE4D (0.58) | PTGS2SLC34A1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2553897 | 0.68 | MEN1 (0.58) | ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552895-B1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | Westfälische Wilhelms Universität Münster (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2552895-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | Westfälische Wilhelms-Universität Münster (DE) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120861-A1 | PYRAZOLE SYNTHESIS BY COUPLING OF CARBOXYLIC ACID DERIVATIVES AND ENAMINES | WESTFÄLISHE WILHELMS-UNIVERSITÄT MÜNSTER (DE) | 2011-10-06 | — | — | WO | disclosed |