Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PDE6A | P16499 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937711 | 0.86 | PDE5A (0.56) | ADORA3PDE5APDE6APDE1BPDE3A | |
| SCHEMBL25221992 | 0.82 | DOT1L (0.41) | ADORA3 | |
| SCHEMBL25269742 | 0.82 | DOT1L (0.41) | ADORA3 | |
| SCHEMBL25679120 | 0.80 | ADORA3 (0.50) | ADORA3GRIA1 | |
| SCHEMBL25598060 | 0.80 | ADORA3 (0.50) | ADORA3GRIA1 | |
| SCHEMBL7320863 | 0.75 | HTR2C (0.41) | ADORA3 | |
| SCHEMBL2402317 | 0.75 | GRIA1 (0.36) | GRIA1 | |
| SCHEMBL3800340 | 0.74 | GRIA1 (0.53) | GRIA1 | |
| SCHEMBL2484426 | 0.72 | TLR7 (0.33) | — | |
| SCHEMBL12574602 | 0.72 | ADORA3 (0.51) | ADORA3GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102184-A1 | BICYCLIC AMINE COMPOUNDS AS CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-06-08 | — | — | WO | disclosed |