⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388343 | 0.69 | — | — | |
| SCHEMBL102331 | 0.67 | PDPK1 (0.59) | — | |
| SCHEMBL15870899 | 0.67 | RIOK2 (0.49) | — | |
| SCHEMBL1986516 | 0.66 | — | — | |
| SCHEMBL31083943 | 0.65 | — | — | |
| SCHEMBL6063 | 0.65 | — | — | |
| Aminothiazole SCHEMBL4962431 | 0.65 | ALDH1A1 (1.00) | — | |
| Aminothiazole SCHEMBL7401 | 0.65 | — | — | |
| Aminothiazole SCHEMBL1136755 | 0.65 | — | — | |
| SCHEMBL31556353 | 0.65 | PDPK1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348048-A | Method for preparing aryl trifluoroethoxyl ether | NAT UNIV DONG HWA | 2016-02-24 | — | — | CN | claimed |
| CN-115197248-B | Novel thiazole boron compound and preparation method and application thereof | 中国科学院化学研究所 | 2025-04-25 | — | — | CN | disclosed |
| CN-115197248-B | Novel thiazole boron compound and preparation method and application thereof | 中国科学院化学研究所 | 2025-04-25 | — | — | CN | disclosed |
| WO-2023187012-A1 | COMPOSITIONS INCLUDING AQUEOUS AMINE BORANE COMPLEXES AND POLYNUCLEOTIDES, AND METHODS OF USING THE SAME TO DETECT METHYLCYTOSINE OR HYDROXYMETHYLCYTOSINE | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023185073-A1 | PARP7 INHIBITOR AND USE THEREOF | 诺沃斯达药业(上海)有限公司 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023114379-A1 | PLPRO INHIBITORS | HUAHAI US INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| EP-4105207-A1 | QUINOLYL PHOSPHINE OXIDE COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2022-12-21 | — | — | EP | disclosed |
| CN-115197248-A | Novel thiazole boron compound and preparation method and application thereof | 中国科学院化学研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-115197248-A | Novel thiazole boron compound and preparation method and application thereof | 中国科学院化学研究所 | 2022-10-18 | — | — | CN | disclosed |
| WO-2021050688-A1 | COMPOUNDS AND USES THEREOF | X-CHEM, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| WO-2012078777-A1 | BICYCLIC COMPOUNDS AS PIM INHIBITORS | AMGEN INC. (US) | 2012-06-14 | — | — | WO | disclosed |
| EP-1363705-B1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2012028757-A1 | FLUORINATED THIAZOLES FOR USE IN TREATING CANCER | UNIVERSITAT DE BARCELONA (ES) | 2012-03-08 | — | — | WO | disclosed |
| WO-2011134280-A1 | COMPOUNDS AS AGONISTS OF S1P1 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |
| EP-1996180-B1 | BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-08-03 | — | — | EP | disclosed |
| US-7910579-B2 | Benzoxazole derivatives | TOHOKU UNIVERSITY (JP) | 2011-03-22 | — | — | US | disclosed |
| WO-2009149188-A1 | COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS | INTERMUNE, INC. (US) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER INC. | 2008-04-17 | — | — | US | disclosed |
| CN-1390139-A | Oncolytic combinations for the treatment of cancer | LILLY CO ELI (US) | 2003-01-08 | — | — | CN | disclosed |