⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14629165 | 0.69 | — | — | |
| SCHEMBL255984 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL26919172 | 0.67 | — | — | |
| SCHEMBL102331 | 0.67 | PDPK1 (0.59) | — | |
| SCHEMBL15870899 | 0.67 | RIOK2 (0.49) | — | |
| SCHEMBL462094 | 0.66 | — | — | |
| Aminothiazole SCHEMBL7401 | 0.65 | — | — | |
| Aminothiazole SCHEMBL4962431 | 0.65 | ALDH1A1 (1.00) | — | |
| Aminothiazole SCHEMBL1136755 | 0.65 | — | — | |
| SCHEMBL31083943 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022491-A1 | FTO INHIBITORS | RPXDS CO., LTD (CN) | 2024-02-01 | — | — | WO | claimed |
| CN-115667265-A | CGAS-inhibiting triazolopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | claimed |
| CN-115197383-A | Thiazolyl covalent organic framework material and application thereof | 苏州大学 | 2022-10-18 | — | — | CN | claimed |
| CN-114763312-A | Method for inducing H halogenation in C-H on benzene ring or heterocyclic ring by ultraviolet light | 中国科学院大连化学物理研究所 | 2022-07-19 | — | — | CN | claimed |
| EP-4021441-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | Trustees of Dartmouth College (US) | 2022-07-06 | — | — | EP | claimed |
| WO-2021042046-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-03-04 | — | — | WO | claimed |
| CN-107698567-B | Isatin azole alcohol compound and preparation method and medical application thereof | 西南大学 | 2020-09-15 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| EP-3395816-A1 | ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2018-10-31 | — | — | EP | claimed |
| US-4788185-A | Cephalosporin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-29 | — | — | US | claimed |
| EP-0255704-A2 | Pyridazinone derivatives, process for their preparation and their use as medicines | Roche Diagnostics GmbH (DE) | 1988-02-10 | — | — | EP | claimed |
| US-4661593-A | Quinoxaline adducts useful as anthelmintics | ANGUS CHEMCIAL COMPANY (US) | 1987-04-28 | — | — | US | claimed |
| EP-0135249-B1 | STYRENE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-12 | — | — | EP | claimed |
| US-4558046-A | ANTIALLERGENS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1985-12-10 | — | — | US | claimed |
| US-4557871-A | Novel styrene derivatives of the general formula | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1985-12-10 | — | — | US | claimed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | claimed |
| EP-0135249-A1 | Styrene derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-03-27 | — | — | EP | claimed |
| US-4016263-A | BACTERICIDES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | claimed |
| US-3957782-A | Pyrazolo [3,4-b]pyrazine-5-carboxylic acids, esters, nitriles and amides | E. R. SQUIBB & SONS, INC. (US) | 1976-05-18 | — | — | US | claimed |