SCHEMBL25599072

SCHEMBL25599072

Ic1cc(-c2ccccc2)cc2c(I)cccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.38
ALDH1A1 P00352 1/20 0.38
DHODH Q02127 2/20 0.37
AXL P30530 2/20 0.36
CDK8 P49336 1/20 0.36
TNIK Q9UKE5 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2C Q14957 1/20 0.36
MAOA P21397 1/20 0.35
KMO O15229 1/20 0.35
PARP1 P09874 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
PTPN1 P18031 1/20 0.33
IKBKB O14920 1/20 0.33
CHUK O15111 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22717152 0.89 ALDH1A1 (0.47) ALDH1A1AXLCDK8TNIKMAOA
SCHEMBL19250892 0.77 HTR6 (0.45) ALDH1A1GRIN2DGRIN2AGRIN2C
SCHEMBL12983173 0.76 PARP1 (0.47) DYRK1AALDH1A1CDK8PARP1PRSS1
SCHEMBL27952459 0.75 ESR1 (0.47) ALDH1A1
SCHEMBL1269977 0.74 NOS1 (0.44) DYRK1AALDH1A1GRIN2DGRIN2AGRIN2C
SCHEMBL30608894 0.74 NOS1 (0.44) DYRK1AALDH1A1GRIN2DGRIN2AGRIN2C
SCHEMBL20623173 0.73 ESR1 (0.47) DYRK1AGRIN2DGRIN2AGRIN2CGSK3B
SCHEMBL21214787 0.73 ESR1 (0.42) ALDH1A1MAOAKMOPRSS1PRSS2
SCHEMBL24729298 0.72 ALDH1A1 (0.50) ALDH1A1MAOACRHBPCRHR2MGLL
SCHEMBL2222869 0.71 GRIN2D (0.45) ALDH1A1GRIN2DGRIN2AGRIN2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096426-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME 주식회사 엘지화학 2023-06-01 WO disclosed
WO-2023085790-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-05-19 WO disclosed