Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.34 |
| ▸ | ITGAV | P06756 | 5/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 3/20 | 0.32 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.32 |
| ▸ | YAP1 | P46937 | 1/20 | 0.31 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25599046 | 0.91 | CXCR2 (0.41) | GPR132CXCR2PTPN1YAP1TRPV1 | |
| SCHEMBL25599221 | 0.90 | GPR132 (0.35) | GPR132ITGB3CXCR2PTPN1ACE | |
| SCHEMBL25599317 | 0.90 | CXCR2 (0.37) | ITGB3ITGB1ITGAVITGA5CXCR2 | |
| SCHEMBL25599540 | 0.89 | PTPN1 (0.36) | GPR132CXCR2PTPN1IDH1YAP1 | |
| SCHEMBL25599311 | 0.89 | ITGB3 (0.32) | ITGB3ITGB1ITGAVITGA5CXCR2 | |
| SCHEMBL25599307 | 0.88 | ITGB1 (0.34) | ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL25599235 | 0.86 | CXCR2 (0.40) | GPR132CXCR2PTPN1MMEACE | |
| SCHEMBL25599570 | 0.86 | CXCR2 (0.40) | GPR132CXCR2PTPN1MMEACE | |
| SCHEMBL25599229 | 0.85 | CXCR2 (0.41) | GPR132CXCR2PTPN1MMEACE | |
| SCHEMBL25599423 | 0.85 | CXCR2 (0.41) | GPR132CXCR2PTPN1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159439-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159439-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | CFTR, AADAC, ARSA | GPR132 750/4885ITGB3 3195/4885ITGB1 4082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.